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KNRUHS Pharmacology Question Papers (2025 to 2021)

KNRUHS Pharmacology is the Phase 2 (2nd Year) theory paper covering general pharmacology, autonomic drugs, cardiovascular drugs, CNS drugs, antimicrobials, and endocrine pharmacology. It is the most classification-heavy and list-dense subject in the MBBS curriculum. GeckoMed provides the complete KNRUHS Pharmacology question paper archive from 2025 to 2021, with topic-wise analysis, exam pattern breakdown, and links to drug classification charts, mnemonics, and important question lists.

Sourced from official KNRUHS exam archives.
Open KNRUHS Pharmacology papers in the GeckoMed app for offline access.

All KNRUHS Pharmacology Question Papers

2025

Year

2025

Paper

KNRUHS Pharmacology Question Paper 2025

Subject

Pharmacology

Phase

2nd Year MBBS

2024

Year

2024

Paper

KNRUHS Pharmacology Question Paper 2024

Subject

Pharmacology

Phase

2nd Year MBBS

2023

Year

2023

Paper

KNRUHS Pharmacology Question Paper 2023

Subject

Pharmacology

Phase

2nd Year MBBS

2022

Year

2022

Paper

KNRUHS Pharmacology Question Paper 2022

Subject

Pharmacology

Phase

2nd Year MBBS

2021

Year

2021

Paper

KNRUHS Pharmacology Question Paper 2021

Subject

Pharmacology

Phase

2nd Year MBBS

KNRUHS Pharmacology Exam Pattern

KNRUHS Pharmacology is a 100-mark theory paper examined in the Phase 2 (2nd Year) professional examination under the NMC CBME format. The paper duration is 3 hours. It is written alongside Pathology, Microbiology, and Forensic Medicine in the 2nd Year professional examination.

The paper follows the NMC CBME structure of long essay questions (LEQ), short essay questions (SEQ), and short answer questions (SAQ). Pharmacology LEQs typically ask for a drug class or mechanism with clinical applications — a beta-blocker question covers mechanism, cardiovascular uses, contraindications, and adverse effects; an antibiotic question covers spectrum, mechanism of resistance, and clinical indications. SEQs cover individual drug profiles or smaller drug classes. SAQs test specific recall — drug doses, named adverse effects, receptor types, and classification lists. The specific mark allocation and question count are visible in the full papers above.

Unlike other Phase 2 subjects, Pharmacology does not have a traditional gross or histology practical. The practical examination at KNRUHS covers pharmacological calculations, prescription writing, and applied viva questions on drug mechanisms and clinical use.


Topic-wise Analysis: KNRUHS Pharmacology (2021 to 2025)

The following topic areas recur across KNRUHS Pharmacology papers from 2021 to 2025. Frequency classification is based on review of papers in the GeckoMed archive.

General and Autonomic Pharmacology

Topic Area

Pharmacokinetics — absorption, Vd, half-life, bioavailability, hepatic first-pass effect

Exam Relevance

Core

Topic Area

Pharmacodynamics — receptor types, agonist vs antagonist, dose-response, therapeutic index

Exam Relevance

Core

Topic Area

Anticholinesterases — neostigmine, physostigmine; mechanism, uses, organophosphate poisoning

Exam Relevance

High-yield

Cardiovascular Pharmacology

Topic Area

Cardiac glycosides — digoxin mechanism, toxicity features, management of toxicity

Exam Relevance

Core

Topic Area

Anticoagulants — heparin (UFH vs LMWH), warfarin (interactions, reversal), DOACs

Exam Relevance

High-yield

Topic Area

Antiarrhythmics — Vaughan Williams classification (Class I-IV), specific drug examples

Exam Relevance

High-yield

CNS Pharmacology

Topic Area

Opioid analgesics — morphine (mechanism, effects, tolerance, withdrawal), naloxone reversal

Exam Relevance

Core

Topic Area

NSAIDs — COX-1 vs COX-2 selectivity, adverse effects (GI, renal, cardiovascular)

Exam Relevance

Core

Topic Area

Antiepileptics — phenytoin, carbamazepine, sodium valproate; mechanisms, adverse effects

Exam Relevance

High-yield

Topic Area

Local anaesthetics — mechanism, ester vs amide classification, toxicity, adrenaline addition

Exam Relevance

High-yield

Topic Area

Antidepressants and antipsychotics — SSRIs vs TCAs, typical vs atypical, EPS

Exam Relevance

Recurring

Antimicrobials

Topic Area

Penicillins and beta-lactams — mechanism, beta-lactamase inhibitors, allergy cross-reactivity

Exam Relevance

Core

Topic Area

Aminoglycosides — streptomycin, gentamicin; ototoxicity, nephrotoxicity, monitoring

Exam Relevance

High-yield

Topic Area

Anti-TB drugs — first-line HRZE regimen, specific adverse effects per drug

Exam Relevance

High-yield

Topic Area

Fluoroquinolones and tetracyclines — mechanism, contraindications, spectrum

Exam Relevance

Recurring

Endocrine and Other Pharmacology

Topic Area

Corticosteroids — classification, mechanism, adverse effects, contraindications

Exam Relevance

Recurring

Note: Frequency data is based on GeckoMed's analysis of KNRUHS Pharmacology papers from 2021 to 2025. Full question paper content is available in the papers above.


Study Tips for KNRUHS Pharmacology

Classification charts before paragraph notes. Pharmacology requires memorising drug classifications, receptor selectivities, and mechanism groupings before individual drug profiles. Starting revision with the GeckoMed classification charts — antihypertensives, antidiabetics, NSAIDs, and antibiotic classification — gives you the organisational framework that makes individual drug profiles easier to place and remember.

Learn each drug as a five-point profile. KNRUHS Pharmacology SAQs and viva questions follow a consistent structure: class, mechanism, uses, adverse effects, contraindications. Building every drug profile in this five-point format — rather than reading paragraphs — creates answers that directly match the marking structure. The pharmacology mnemonics PDF covers the high-yield adverse effect mnemonics that prevent confusing drug profiles under exam pressure.

Adverse effects are the highest-yield SAQ category. KNRUHS Pharmacology short answer questions disproportionately ask for adverse effects — digoxin toxicity features, aminoglycoside ototoxicity, phenytoin adverse effects, metformin lactic acidosis, steroid adverse effects. Maintaining a separate adverse effects list for the 20 most important drugs is more exam-efficient than revising mechanisms and uses alone.

Anti-TB drugs deserve a dedicated revision session. The HRZE first-line regimen and its drug-specific adverse effects — hepatotoxicity (isoniazid, pyrazinamide), optic neuritis (ethambutol), peripheral neuropathy (isoniazid), orange urine (rifampicin) — are tested as a cluster in KNRUHS papers. Revising all four drugs together in one session prevents mix-ups between their adverse effect profiles.

Antimicrobial coverage is directly testable. Antibiotic spectrum, mechanism of resistance, and clinical indications are asked as structured SAQs across most KNRUHS Pharmacology papers. The antibiotic sensitivity chart and antibiotic classification chart build this knowledge in a format that matches the question format — drug class, spectrum, organisms covered — rather than requiring extraction from a textbook paragraph.

Pharmacology knowledge compounds across subjects. Drug mechanisms and adverse effects tested in KNRUHS Pharmacology reappear in Final Year General Medicine (antihypertensive selection, DKA management drugs), General Surgery (pre-operative medications, DVT prophylaxis), and OBG (oxytocics, tocolytics, antihypertensives in pregnancy). Investing in accurate Pharmacology revision in 2nd Year reduces the revision burden across three Final Year subjects simultaneously.


Frequently Asked Questions

Are KNRUHS Pharmacology question papers free to download on GeckoMed?

Yes. All KNRUHS Pharmacology question papers from 2021 to 2025 are free to view on the GeckoMed website. The GeckoMed app provides offline access and PDF download after a 4-day free trial, followed by an annual subscription.

Does the KNRUHS Pharmacology paper follow the NMC CBME format?

Yes. KNRUHS conducts Pharmacology examinations under the NMC Competency Based Medical Education framework. The paper includes long essay questions, short essay questions, and short answer questions covering general pharmacology, autonomic pharmacology, cardiovascular, CNS, antimicrobial, and endocrine drug classes as per the Phase 2 CBME syllabus.

Does Pharmacology have a practical examination at KNRUHS?

Yes, but its format differs from other Phase 2 subjects. Rather than gross specimen or slide identification, the Pharmacology practical at KNRUHS covers pharmacological calculations, prescription writing, and applied viva questions on drug mechanisms, adverse effects, and clinical use.

What is the most important topic in KNRUHS Pharmacology?

Based on analysis of KNRUHS Pharmacology papers from 2021 to 2025, antihypertensives, cardiac glycosides (digoxin), opioid analgesics, anti-TB drug adverse effects, and insulin types are among the most consistently tested topics. General pharmacokinetics and pharmacodynamics underpin the entire paper and appear in both LEQs and SAQs across all paper years.

Are KNRUHS Pharmacology papers useful for students at other universities?

Yes. The NMC CBME framework sets a common Pharmacology syllabus for all Indian medical universities. Topics recurring in KNRUHS papers — antihypertensives, antimicrobials, CNS drugs, endocrine pharmacology — appear at RGUHS, TNMGRMU, and other universities. Students at other universities should also review their own university's papers alongside the KNRUHS archive.

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