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General Medicine for MBBS: Notes, PYQs and Viva

General Medicine is one of the four Final Year subjects in the NMC Competency Based Medical Education (CBME) programme, examined in the Phase 3 Part 2 professional examination alongside General Surgery, Obstetrics and Gynaecology (OBG), and Paediatrics. It is the broadest subject in the MBBS curriculum — covering cardiovascular, respiratory, gastroenterological, renal, neurological, endocrine, haematological, rheumatological, and infectious disease medicine across both theory and a long-case clinical examination. GeckoMed provides General Medicine PYQs across all seven target universities, important question lists, and condition-wise topic guides for the highest-yield diseases.

Open General Medicine resources in the GeckoMed app

What Is General Medicine in MBBS?

General Medicine in the MBBS Final Year covers the clinical management of adult disease across all organ systems. The syllabus is structured to train students to take a focused history, conduct a systematic examination, formulate a differential diagnosis, request and interpret investigations, and outline a management plan — the core competencies assessed in the long-case practical examination.

The subject spans multiple clinical domains. Cardiovascular disease covers ischaemic heart disease (acute myocardial infarction, stable angina), hypertension and its complications, heart failure, rheumatic fever, infective endocarditis, and common arrhythmias. Respiratory medicine covers asthma, chronic obstructive pulmonary disease (COPD), tuberculosis, pneumonia, pleural effusion, and pulmonary malignancy. Gastroenterology covers peptic ulcer disease, gastro-oesophageal reflux, liver cirrhosis and its complications, jaundice (differential and workup), hepatitis, pancreatitis, and malabsorption. Nephrology covers acute kidney injury, chronic kidney disease, glomerulonephritis, nephrotic syndrome, and urinary tract infections.

Neurology covers stroke (ischaemic versus haemorrhagic), epilepsy, meningitis, Parkinson's disease, and raised intracranial pressure. Endocrinology — a very high-yield area — covers diabetes mellitus (Type 1, Type 2, DKA, HHS, long-term complications), thyroid disorders (hypothyroidism, hyperthyroidism, goitre), and basics of adrenal and pituitary disease. Haematology covers anaemia classification and management, leukaemia basics, ITP, and haemolytic disorders. Infectious diseases — particularly relevant to the Indian clinical context — covers malaria, dengue, typhoid, leptospirosis, and HIV.

The General Medicine practical examination includes a long-case component, where students are given time to examine a patient and present the case to the examiner, and a short-case or spot diagnosis component. The viva tests applied clinical knowledge and investigation interpretation.


General Medicine Question Papers by University

GeckoMed provides General Medicine question papers across all seven target universities. Tier-1 universities (RGUHS, KNRUHS, TNMGRMU) include papers from 2025, 2024, 2023, and 2021. Non-Tier-1 universities (NTRUHS, WBUHS, KUHS, RUHS) include papers from 2025, 2024, and 2023.

General Medicine Important Questions

Important question lists for General Medicine are compiled from PYQ frequency analysis across all seven universities. These pages highlight which topics and question types have been repeated most across paper years — essential for prioritising revision in the final weeks before the professional exam.

General Medicine Notes and Study Material

GeckoMed's medical topics library covers 18 conditions that are high-yield in Final Year General Medicine written papers and clinical examinations. Each condition guide includes definition, aetiology, pathophysiology, clinical features, investigations, management, complications, and PYQ links:

Cardiovascular and Respiratory

Myocardial Infarction | Hypertension | Congestive Heart Failure | Asthma | Tuberculosis | Pneumonia

Gastroenterology and Hepatology

Peptic Ulcer | Liver Cirrhosis | Jaundice

Neurology

Stroke | Epilepsy | Meningitis

Endocrine and Haematology

Diabetes Mellitus | Thyroid Disorders | Anaemia

Infectious Diseases

Malaria | Dengue | Typhoid | Leprosy

Also useful for General Medicine revision:

Subject-level General Medicine notes are available in the GeckoMed app. Website notes pages will be added as they publish.


General Medicine Viva and Practical Preparation

The General Medicine Final Year practical examination is among the most clinically demanding assessments in the MBBS programme. The long case requires students to take a full history, examine the patient systematically, and present a structured case with a differential diagnosis, investigation plan, and management outline — all within a fixed time. The examiner then asks applied questions on the case and on related topics.

General Medicine viva questions and a long-case preparation guide are available in the GeckoMed app. A dedicated website viva page for General Medicine will be added to the Viva section when published.

For applied viva revision, the condition guides above — particularly for Diabetes Mellitus, Myocardial Infarction, Stroke, and Liver Cirrhosis — are structured with the clinical features and management sections written to match the depth expected in Final Year long-case presentations and viva answers.


Frequently Asked Questions

How many papers does General Medicine have in Final Year MBBS?

General Medicine is assessed in a single theory paper and a separate clinical practical examination in the Phase 3 Part 2 Final Year professional examination. The practical includes a long case, short cases or spot diagnoses, and a viva with the examiner. General Medicine is typically the longest and most content-heavy paper in the Final Year examination.

What are the most important topics in General Medicine for university exams?

Based on PYQ patterns across all seven GeckoMed universities, the consistently high-yield topics are: diabetes mellitus (DKA, management, complications), hypertension (classification, target organ damage, antihypertensive selection), ischaemic heart disease (ECG changes, management of AMI), tuberculosis (diagnosis, RNTCP regimen, drug adverse effects), stroke (ischaemic versus haemorrhagic, thrombolysis), liver cirrhosis (Child-Pugh classification, complications), and infectious diseases (malaria, dengue — tropical disease management is particularly high-yield at South Indian universities).

Does General Medicine overlap with other Final Year subjects?

Yes, significantly. Surgical complications of medical conditions (GI bleeding, jaundice, pancreatitis) appear across General Medicine and General Surgery papers. Medical complications of pregnancy (gestational diabetes, hypertensive disorders, anaemia) overlap with OBG. Infectious disease epidemiology and control overlap with Community Medicine. Paediatric presentations of the same conditions studied in General Medicine appear in Paediatrics papers. Revising topics like tuberculosis, malaria, and diabetic complications benefits multiple subjects simultaneously.

Are the question paper formats the same across all seven universities?

The NMC CBME framework defines a common syllabus, but examination formats vary. RGUHS and KNRUHS typically use a combination of long answer, short answer, and structured essay questions. TNMGRMU and NTRUHS formats also vary in their balance between short and long answers. Reviewing papers from your specific university alongside the national archive gives the most accurate picture of the format you will face.

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