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Tamil Nadu Dr. M.G.R. Medical University (TNMGRMU)
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TNMGRMU Biochemistry Question Papers (2025-2021)
Four years of Tamil Nadu Dr. M.G.R. Medical University (TNMGRMU) Biochemistry question papers, available to view online or download via the GeckoMed app. Papers from 2025, 2024, 2023, 2022, and 2021 are included, with topic-wise analysis and most-repeated question highlights available in the app.
Sourced from the TNMGRMU official exam archive | Phase 1 / 1st Year MBBS | Updated 2026
Open Free in the GeckoMed App]TNMGRMU Biochemistry Question Papers: All Available Years
Papers below cover all confirmed years for the TNMGRMU Phase 1 / 1st Year Biochemistry theory paper.
2025
| Field | Detail |
|---|---|
| University | Tamil Nadu Dr. M.G.R. Medical University (TNMGRMU) |
| Subject | Biochemistry |
| Year | 2025 |
| Phase | Phase 1 / 1st Year MBBS |
| Total Marks | 100 |
| Duration | 3 hours |
| Paper Type | Theory |
| View | View Online |
Field
Subject
Detail
Biochemistry
Field
Year
Detail
2025
Field
Phase
Detail
Phase 1 / 1st Year MBBS
Field
Total Marks
Detail
100
Field
Duration
Detail
3 hours
Field
Paper Type
Detail
Theory
Field
View
Detail
2024
| Field | Detail |
|---|---|
| University | Tamil Nadu Dr. M.G.R. Medical University (TNMGRMU) |
| Subject | Biochemistry |
| Year | 2024 |
| Phase | Phase 1 / 1st Year MBBS |
| Total Marks | 100 |
| Duration | 3 hours |
| Paper Type | Theory |
| View | View Online |
Field
University
Detail
Tamil Nadu Dr. M.G.R. Medical University (TNMGRMU)
Field
Subject
Detail
Biochemistry
Field
Year
Detail
2024
Field
Phase
Detail
Phase 1 / 1st Year MBBS
Field
Total Marks
Detail
100
Field
Duration
Detail
3 hours
Field
Paper Type
Detail
Theory
Field
View
Detail
2023
| Field | Detail |
|---|---|
| University | Tamil Nadu Dr. M.G.R. Medical University (TNMGRMU) |
| Subject | Biochemistry |
| Year | 2023 |
| Phase | Phase 1 / 1st Year MBBS |
| Total Marks | 100 |
| Duration | 3 hours |
| Paper Type | Theory |
| View | View Online |
Field
University
Detail
Tamil Nadu Dr. M.G.R. Medical University (TNMGRMU)
Field
Subject
Detail
Biochemistry
Field
Year
Detail
2023
Field
Phase
Detail
Phase 1 / 1st Year MBBS
Field
Total Marks
Detail
100
Field
Duration
Detail
3 hours
Field
Paper Type
Detail
Theory
Field
View
Detail
2022
| Field | Detail |
|---|---|
| University | Tamil Nadu Dr. M.G.R. Medical University (TNMGRMU) |
| Subject | Biochemistry |
| Year | 2023 |
| Phase | Phase 1 / 1st Year MBBS |
| Total Marks | 100 |
| Duration | 3 hours |
| Paper Type | Theory |
| View | View Online |
Field
University
Detail
Tamil Nadu Dr. M.G.R. Medical University (TNMGRMU)
Field
Subject
Detail
Biochemistry
Field
Year
Detail
2023
Field
Phase
Detail
Phase 1 / 1st Year MBBS
Field
Total Marks
Detail
100
Field
Duration
Detail
3 hours
Field
Paper Type
Detail
Theory
Field
View
Detail
2021
| Field | Detail |
|---|---|
| University | Tamil Nadu Dr. M.G.R. Medical University (TNMGRMU) |
| Subject | Biochemistry |
| Year | 2021 |
| Phase | Phase 1 / 1st Year MBBS |
| Total Marks | 100 |
| Duration | 3 hours |
| Paper Type | Theory |
| View | View Online |
Field
University
Detail
Tamil Nadu Dr. M.G.R. Medical University (TNMGRMU)
Field
Subject
Detail
Biochemistry
Field
Year
Detail
2021
Field
Phase
Detail
Phase 1 / 1st Year MBBS
Field
Total Marks
Detail
100
Field
Duration
Detail
3 hours
Field
Paper Type
Detail
Theory
Field
View
Detail
TNMGRMU Biochemistry Exam Pattern
TNMGRMU Biochemistry theory papers follow the National Medical Commission (NMC) Competency-Based Medical Education (CBME) format. The paper covers metabolic pathways, molecular biology, clinical biochemistry, vitamins, and enzymes across long and short answer formats.
| Component | Detail |
|---|---|
| Total Marks | 100 (theory paper) |
| Duration | 3 hours |
| Question Types | Long Answer Questions (LAQs) and Short Answer Questions (SAQs) |
| Curriculum | NMC CBME |
| Subject Coverage | Carbohydrate, Lipid and Protein Metabolism, Enzymes, Vitamins, Molecular Biology, Clinical Biochemistry |
| Practical Assessment | Separate from the theory paper |
Component
Total Marks
Detail
100 (theory paper)
Component
Duration
Detail
3 hours
Component
Question Types
Detail
Long Answer Questions (LAQs) and Short Answer Questions (SAQs)
Component
Curriculum
Detail
NMC CBME
Component
Subject Coverage
Detail
Carbohydrate, Lipid and Protein Metabolism, Enzymes, Vitamins, Molecular Biology, Clinical Biochemistry
Component
Practical Assessment
Detail
Separate from the theory paper
Biochemistry under the NMC CBME curriculum increasingly connects metabolic pathways to clinical conditions. A question on glycolysis may ask you to explain the step blocked in a specific enzyme deficiency. A lipid metabolism LAQ may require you to link fatty acid oxidation to ketoacidosis. An enzyme question will almost always ask for clinical applications alongside the mechanism.
When practising TNMGRMU Biochemistry papers, do not treat pathways in isolation. Understand which disorders arise from which enzymatic blocks, and be ready to write both the normal mechanism and the clinical consequence in the same answer.
Most-Repeated Topics in TNMGRMU Biochemistry Papers
Based on analysis of TNMGRMU Biochemistry papers from 2021 to 2025. For year-by-year question-level data, open the GeckoMed app.
| Topic Area | Priority | Study Resource |
|---|---|---|
| Glycolysis -- steps, enzymes, energy yield, regulation | High | Biochemistry Notes |
| TCA (Krebs) cycle -- reactions, regulation, clinical significance | High | Krebs Cycle Diagram |
| Beta-oxidation of fatty acids -- steps, energy yield | High | Biochemistry Notes |
| Urea cycle -- steps, enzymes, disorders (hyperammonaemia) | High | Biochemistry Notes |
| Enzyme kinetics -- Michaelis-Menten, Km, Vmax, inhibition types | High | Biochemistry Notes |
| Isoenzymes -- LDH, CK, AST, ALT; clinical use in diagnosis | High | Biochemistry Viva |
| Cholesterol -- synthesis, transport, lipoproteins (HDL, LDL, VLDL) | High | Biochemistry Notes |
| Gluconeogenesis -- substrates, steps, regulation, clinical significance | Regular | Biochemistry Notes |
| Ketone body formation and utilisation -- diabetic ketoacidosis | Regular | Biochemistry Notes |
| DNA structure and replication -- Watson-Crick model, semi-conservative replication | Regular | Biochemistry Notes |
| Transcription and translation -- central dogma, genetic code | Regular | Biochemistry Notes |
| Iron metabolism -- absorption, transport, ferritin, transferrin, deficiency | Regular | Biochemistry Notes |
| Fat-soluble vitamins -- A, D, E, K; sources, functions, deficiency diseases | Regular | Biochemistry Notes |
| Water-soluble vitamins -- B complex and C; deficiency diseases | Periodic | Biochemistry Notes |
| HMP shunt -- significance, disorders (G6PD deficiency) | Periodic | Biochemistry Notes |
| Liver function tests -- bilirubin, albumin, transaminases, clinical interpretation | Periodic | Biochemistry Practical Viva |
Topic Area
Glycolysis -- steps, enzymes, energy yield, regulation
Priority
High
Study Resource
Topic Area
TCA (Krebs) cycle -- reactions, regulation, clinical significance
Priority
High
Study Resource
Topic Area
Beta-oxidation of fatty acids -- steps, energy yield
Priority
High
Study Resource
Topic Area
Urea cycle -- steps, enzymes, disorders (hyperammonaemia)
Priority
High
Study Resource
Topic Area
Enzyme kinetics -- Michaelis-Menten, Km, Vmax, inhibition types
Priority
High
Study Resource
Topic Area
Isoenzymes -- LDH, CK, AST, ALT; clinical use in diagnosis
Priority
High
Study Resource
Topic Area
Cholesterol -- synthesis, transport, lipoproteins (HDL, LDL, VLDL)
Priority
High
Study Resource
Topic Area
Gluconeogenesis -- substrates, steps, regulation, clinical significance
Priority
Regular
Study Resource
Topic Area
Ketone body formation and utilisation -- diabetic ketoacidosis
Priority
Regular
Study Resource
Topic Area
DNA structure and replication -- Watson-Crick model, semi-conservative replication
Priority
Regular
Study Resource
Topic Area
Transcription and translation -- central dogma, genetic code
Priority
Regular
Study Resource
Topic Area
Iron metabolism -- absorption, transport, ferritin, transferrin, deficiency
Priority
Regular
Study Resource
Topic Area
Fat-soluble vitamins -- A, D, E, K; sources, functions, deficiency diseases
Priority
Regular
Study Resource
Topic Area
Water-soluble vitamins -- B complex and C; deficiency diseases
Priority
Periodic
Study Resource
Topic Area
HMP shunt -- significance, disorders (G6PD deficiency)
Priority
Periodic
Study Resource
Topic Area
Liver function tests -- bilirubin, albumin, transaminases, clinical interpretation
Priority
Periodic
Study Resource
High = appears consistently across multiple years in the archive. Regular = appears in most but not all years analysed. Periodic = appears in some years; covers enough marks to be worth revising.
These categories reflect broad pattern trends, not verified per-paper counts. Cross-check against each year's paper in the GeckoMed app before finalising your revision list.
How to Study TNMGRMU Biochemistry Papers Effectively
- Draw every pathway before writing about it. Biochemistry LAQs are pathway questions. Before writing a single word of your answer, sketch the pathway with enzymes, cofactors, and regulatory steps. A labelled diagram in the answer earns marks on its own and also structures the rest of your response. Practise drawing glycolysis, the TCA cycle, beta-oxidation, and the urea cycle from memory until they take under three minutes each.
- Learn disorders alongside each pathway. Every major pathway has at least one associated disorder that TNMGRMU questions target. Glycolysis connects to haemolytic anaemia (pyruvate kinase deficiency). The urea cycle connects to hyperammonaemia. Beta-oxidation connects to ketoacidosis. Knowing the clinical connection makes both the mechanism question and the SAQ on the disorder answerable from the same block of revision.
- Treat enzymes as a standalone revision unit. Enzyme kinetics, inhibition types, isoenzymes, and allosteric regulation appear across multiple question types in TNMGRMU papers. Revise all enzyme concepts together rather than scattering them across individual pathway chapters. This unit also prepares you well for the clinical biochemistry SAQs on liver function and cardiac markers.
- Work through all four years in sequence. Start from 2021 to map the foundational topics, then move forward. Metabolism pathways and molecular biology appear consistently across years, but the balance between LAQs and SAQs, and the specific clinical angles used, shifts across the 2023-2025 papers. Completing all four years gives you a clear view of both stable and evolving question patterns.
- Pair written papers with practical viva prep. Biochemistry practical exams at TNMGRMU test skills such as urine analysis, blood glucose estimation, and protein qualitative tests. These same areas appear as SAQs in theory papers. Working through Biochemistry Practical Viva Questions alongside theory papers covers both assessments efficiently.
- Memorise normal lab values for clinical biochemistry. Serum bilirubin, albumin, transaminase ranges, fasting blood glucose, and creatinine values appear in clinical biochemistry questions. Knowing the normal range is often the first step required in the answer before you can interpret an abnormal result.
- Use cross-university papers once TNMGRMU papers are complete. If you need additional practice after working through all four TNMGRMU papers, try RGUHS Biochemistry Question Papers or KNRUHS Biochemistry Question Papers. Pathway questions have high overlap across universities because the NMC CBME syllabus is standardised nationally.
Frequently Asked Questions
How many years of TNMGRMU Biochemistry question papers are available on GeckoMed?
GeckoMed has TNMGRMU Biochemistry papers for 2025, 2024, 2023, 2022, and 2021. TNMGRMU is a Tier-1 university on GeckoMed, so all 14 MBBS subjects have four-year coverage.
Are TNMGRMU Biochemistry papers available with answers?
Yes. The paper is available to view or download via the GeckoMed app. Topic-wise answer guides and most-repeated question analysis are included alongside each paper in the app.
Does the TNMGRMU Biochemistry paper follow the NMC CBME format?
Yes. TNMGRMU Biochemistry theory papers are conducted under the NMC CBME curriculum. The paper covers carbohydrate, lipid, and protein metabolism, enzymes, vitamins, molecular biology, and clinical biochemistry through LAQs and SAQs.
Which topics repeat most often in TNMGRMU Biochemistry papers?
Based on analysis of papers from 2021 to 2025, glycolysis, the TCA cycle, beta-oxidation, the urea cycle, enzyme kinetics, isoenzymes, and cholesterol metabolism appear most consistently. Full topic-frequency data is available in the GeckoMed app.
Can I use other universities' Biochemistry papers to prepare for TNMGRMU?
Yes. Pathway and enzyme topics are standardised across universities under the NMC CBME curriculum, so cross-university practice is useful. Prioritise TNMGRMU papers for format and question style familiarity, then supplement with RGUHS or KNRUHS papers once you have worked through all four TNMGRMU years.
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